"The Losers" centers upon the members of an elite U.S. Special Forces unit sent into the Bolivian jungle on a search and destroy mission. The team-Clay, Jensen, Roque, Pooch and Cougar -find themselves the target of a lethal betrayal instigated from inside by a powerful enemy known only as Max. Presumed dead, the group makes plans to even the score when they're joined by the mysterious Aisha, a beautiful operative with her own agenda. Working together, they must remain deep undercover while tracking the heavily-guarded Max, a ruthless man bent on embroiling the world in a new high-tech global war.